Everything about ceesdekker
Everything about ceesdekker
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‘The next is nanopores, and that is our oldest line of exploration and that has now brought about DNA sequencers based upon nanopores. We pull particular person DNA strands via a nanopore and might then read through off the nucleotide sequence. Extremely not too long ago, we even managed to go through out just one protein for the first time applying this technique. But this line of investigate is don't just about producing equipment, but additionally about genuine Organic issues.
Our team reports bacterial cell division and is aiming to represent a ‘bottom up biology’ in synthetic cells that can autonomously divide. Our most important fascination lies in cell division, chromatin structure, and spatial Regulate.
, Groningen scientists existing the effects in their endeavours to make labs much more sustainable and provide techniques for other labs.
2007, initially real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence size of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and 1st ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Our exploration ranges within the biophysics of DNA to artificial cells and outside of. You should take a look underneath for the spectrum of our latest jobs.
Several relevant developments adopted, the place our team recognized unique transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-basic principle Digital circuits.
Illustration (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is displayed.
‘Indeed, I have an understanding of folks were being shocked at enough time. At the end of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to admit that it experienced turn into a bit bored, I didn’t understand much any more. The sector went extra into the application aspect, how you could potentially integrate nanotubes into electronic circuits.
Resolving the action dimensions in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-generating method
‘The concept There's this type of matter to be a beginning, an enormous bang, is previously a fascinating signpost to look at that there was a creator. But much more typically, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is usually a naturalistic worldview: essentially, you will find only atoms and organic forces that we will measure.
Later on we spoke again briefly since Dekker felt that our dialogue of his cees dekker religion immediately became purely philosophical, whereas In addition, it concretely can help him in his do the job.
Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy approaches
Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments